Research Interests

Categories:
  • Determining molecular and genetic risk factors of cancer initiation and progression
  • Assessing the interplay between obesity and cancer
  • Understanding the genetic etiology of Type 2 diabetes

HISTORY & EDUCATION

Degrees
  • Case Western Reserve University, Ph.D., 2006
  • Case Western Reserve University, MPH, 2004
  • Cornell University, BS, 1997
Fellowships
  • Harvard School of Public Health (NCI Post-Doctoral Fellowship), 2006 – 2008

MEMBERSHIPS & AFFILIATIONS

Memberships
  • American Association for Cancer Research
  • International Genetic Epidemiology Society

PUBLICATIONS

  • Li L, Yu H, Schumacher F, Casey G, Witte JS.
    Relation of serum insulin-like growth factor-I (IGF-I) and IGF binding protein-3 to risk of prostate cancer (United States).
    Cancer Causes Control 14:721-6, 2003.
  • Xing C, Schumacher FR, Conti DV, Witte JS.
    Comparison of missing data approaches in linkage analysis.
    BMC Genet. 4 Suppl 1:S44, 2003.
  • Xing C, Schumacher FR, Xing G, Lu Q, Wang T, Elston RC.
    Comparison of microsatellites, single-nucleotide polymorphisms (SNPs) and composite markers derived from SNPs in linkage analysis.
    BMC Genet. 6 Suppl 1:S29, 2005.
  • Cicek MS, Liu X, Schumacher FR, Casey G, Witte JS.
    Vitamin D receptor genotypes/haplotypes and prostate cancer risk.
    Cancer Epidemiol Biomarkers Prev. 15: 2549-52, 2006.
  • Liu X, Schumacher FR, Plummer SJ, Jorgenson E, Casey G, Witte JS.
    Trans fatty acid intake and increased risk of advanced prostate cancer: modification by RNASEL R462Q variant.
    Carcinogenesis. 28: 1232-6, 2007.
  • Yeager M, Orr N, Hayes RB, Jacobs K, Kraft P, Wacholder S, Minichiello MJ, Fernhead P, Yu K, Chatterjee N, Welch R, Staats B, Calle EE, Feigelson H, Thun M, Albanes D, Virtamo J, Weinstesin S, Schumacher FR, Giovannucci E, et al.
    Genome-wide association study of prostate cancer identifies a second locus at 8q24.
    Nat Genet. 39:645-9, 2007.
  • Schumacher FR, Feigelson HS, Cox DG, Haiman CA, Albanes D, et al.:
    A common 8q24 variant in breast and prostate cancer from a large nested case-control study. Can Res. 67: 2951-56, 2007.
  • Setiawan VW, Schumacher FR, Haiman CA, Stram DP. Feoge;spm JS.
    Cjampcl SK et al. CYP17 genetic variation and risk of breast and prostate cancer.
    CEBP 16:2237-46, 2007.
  • Swartz MD, Thomas DC, Daw EW, Albers K, Charlesworth JC, Dyer TC, Fridely BL, Govil M, Kraft P, Kwon S, Logue MW, Oh C, Pique-Regi R, Saba L, Schumacher FR, Uh HW:
    Model selection and Bayesian methods in statistical genetics: summary of group 11 contributions to Genetic Analysis Workshop 15.
    Genet Epidemiol. 31 Suppl 1: S96-102, 2007.
  • Schumacher FR and Kraft P. A Bayesian latent class analysis for whole-genome association analyses: an illustration using the GAW 15 simulated rheumatoid arthritis dense scan data.
    BMC Proceedings 1 2007; Suppl 1: 112.
  • Thomas G, Jacobs KB, Yeager M, Kraft P, Wacholder S, Orr N, Yu K, Chatterjee N, Welch R, Hutchinson A, Crenshaw A, Cancel-Tassin G, Staats BJ, Wang Z, Gonzalez-Bosquet J, Fang J, Deng X, Berndt SI, Calle EE, Feigelson HS, Thun MJ, Rodriquez C, Albanes D, Virtamo J, Weinstein S, Schumacher FR, Giovannucci E, et al.:
    Multiple novel loci identified in a genome-wide study of prostate cancer.
    Nat Genet. 40: 310-315, 2008.
  • Lettre G, Jackson AU, Gieger C, Schumacher FR, Berndt SI et al.:
    Genome-wide association studies identify ten novel loci for height and highlight new biological pathways in human growth.
    Nat Genet. 40: 584-591, 2008.
  • Penney KL, Salinas CA, Pomerantz MM, Schumacher FR, et al. Evaluation of 8q24 and 17q risk loci and prostate cancer mortality. Clin Cancer Res 2009; 15: 3223-30.
  • Lou H, Yeager M, Li H, Bosquet JG, Hayes RB, Orr N, Yu K, Hutchinson A, Jacobs K, Kraft P, Wacholder S, Chatterjee N, Feigelson H, Thun M, Diver WR, Albanes D, Virtamo J, Weinstein S, Ma J, Gaziano JM, Stampfer MJ, Schumacher FR, et al. Fine mapping and functional analysis of a common variant in MSMB on chromosome 10q11.2 associated with prostate cancer susceptibility. PNAS 2009; 106: 7933-8. PMCID: PMC2671324.
  • Stark J, Wiklund F, Gronberg H, Schumacher FR, et al. Toll-like receptor signaling pathway variants and prostate cancer mortality. CEBP 2009; 18: 1859-63.
  • Mucci LA, Stark JR, Figg W, Schumacher FR, et al. Polymorphism in endostatin, an angiogenesis inhibitor, and prostate cancer risk and survival: a prospective study. Int J Cancer 2009; 125: 1143-6.
  • Pomerantz MM, Beckwith CA, Regan MM, Wyman SK, Petrovics G, Chen Y, Hawksworth DJ, Schumacher FR, et al. Evaluation of the 8q24 prostate cancer locus and MYC expression. Cancer Res 2009; 69: 5568-74.
  • Ahn J, Schumacher FR, Berndt SI, et al. Quantitative trait loci predicting circulating sex steroid hormones in men from the NCI-Breast and Prostate Cancer Cohort Consortium (BPC3). Hum Mol Genet 2009; 18: 3749-57. PMCID: PMC2742399
  • Yeager M, Chatterjee N, Ciampa J, Jacobs KB, Gonzalez-Bosquet J, Hayes RB, Kraft P, Wacholder S, Orr N, Berndt S, Yu K, Hutchinson A, Wang Z, Amundadottir L, Feigelson HS, Thun MJ, Diver WR, Albanes D, Virtamo J, Weinstein S, Schumacher FR, et al. Identification of a new prostate cancer susceptibility locus on chromosome 8q24. Nat Genet 2009; 41: 1055-7.
  • Travis RC, Schumacher FR, Hirschhorn JN, et al. CYP19A1 genetic variation in relation to prostate cancer risk and circulating sex hormone concentrations in men from the breast and prostate cancer cohort consortium. CEBP 2009; 18: 2734-44. PMCID: PMC2812905
  • Shtir C, Pique-Regi R, Siegmund K, Morrison J, Schumacher FR, Marjoram P. Copy number variation in the Framingham Heart Study. BMC Proceedings 2009; Suppl 7: S133 PMCID: PMC2795907
  • Koutros S, Schumacher FR, Hayes RB, et al. Pooled analysis of phosphatidylinositol 3-kinase pathway variants and risk of prostate cancer. Cancer Res 2010; 70: 2389-96. PMCID: PMC2840184
  • Schumacher FR, Cheng I, Freedman ML, Mucci L, Allen N, Pollak M, Hayes RB, Ma J: Common variants in IGF1, IGFBP1, and IGFBP3 are associated with blood IGF levels and prostate cancer risk among caucasians. Human Molecular Genetics 2010. In press

Direct link to profile: http://keck.usc.edu/profiles?facid=3859