I was born and grew up in Central New Jersey and graduated from North Plainfield High School. I was fortunate to be selected for the first year of the combined B.A.-M.D. 6-year program at Boston University in 1961 and graduated with a B.A. and M.D. in 1967. I then had my Pediatric training at the University of Minnesota Hospitals before then joining the NCI as a Clinical Associate in the Leukemia Branch from 1969-72. I was recruited to Childrens Hospital and U.S.C. in 1972 as an Assistant Professor of Pediatrics by Dr. Myron Karon and was appointed the Head of the Division of Hematology-Oncology in 1976 after Dr. Karon

Research Interests

My primary interests are in clinical therapeutic and supportive care research in pediatric oncology where my focus has been in neuroblastoma, non-hodgkins lymphoma, Ewings Sarcoma, Acute lymphoblastic leukemia and brain tumors.
  • Clinical Trials in Pediatric Cancer
  • Developmental Therapeutics in Pediatric Cancer
  • Psychosocial aspects of Pediatric Cancer

Clinical Interests

  • Pediatric Hematology-Oncology
  • Infection in the Compromised Host


  • Boston University, MD, 1967
  • University of Minnesota Hospitals (Pediatrics), 1967 – 1968
  • University of Minnesota Hospitals (Pedatrics), 1968 – 1969
  • Leukemia Branch, National Cancer Institute, NIH (Pediatric Oncology), 1969 – 1972
Board Certification
  • American Board of Pediatrics, 1973
  • Specialty Board Certified Pediatric Hematology-Oncology, 1976


  • Massachusetts Medical Society Prize, 1967
  • University Hospital Prize, 1967
  • Phi Beta Kappa, 1966
  • University of Minnesota Medical Students Resident Award, 1969
  • Collegium of Distinguished Alumni Award, CAS, Boston University, 1984
  • Distinguished Alumni Award, MED, Boston University, 1997
  • Boston University Alumni Award, 2003
  • Concern Foundation Honoree, 1991
  • El Sueno de Esparanza, Padres Contra El Cancer, 2000
  • Crystal Heart Award, Chase Foundation, 1991
  • Israel Cancer Research Foundation Honoree, 1994
  • Distinguished Service Award, CHLA, 1984
  • National Caring Award, The Caring Institute, 2001
  • The Kim Hill Award, Ronald McDonald House, 1990
  • Honorary Professor of Pediatric, Chinese General Hospital of the People's Liberation Army, Bejing, P.R.C., 2000
  • ASCO
  • AACR
  • APS
  • SPR
  • ISPO
  • AACE
  • AAS
  • AMA
Clinical Affiliation
  • Childrens Hospital Los Angeles
  • Ventura County Medical Center
  • Huntington Memorial Hospital, Pasadena


  • Selected Publications

    Siegel SE, Levine AS. Virus-specific Nucleic Acids in Simian Virus 40-transformed Hamster Cell Clones varying in Oncogenic Potential. J. Nat. Cancer Inst., 49: 1667-1673,1972.

  • Nachum R, Lipsey A, Siegel SE. Rapid Detection of Gram-Negative Bacterial Meningitis by the Limulus Lysate Test. New Eng. J. Med., 289: 931-934, 1973.
  • Siegel SE, Nesbit ME, Baehner R, Sather H, Hammond GD. Pneumonia during Therapy of Childhood Acute Lymphoblastic Leukemia. Am. J. Dis. Child., 134: 28-34, 1980.
  • Seeger RC, Brodeur GM, Sather H, Dalton A, Siegel SE, Wong KY, Hammond GD. Association of Multiple Copies of the N-myc Oncogene with rapid Progression of Neuroblastomas. New Eng. J. Med., 313: 1111-1116, 1985.
  • Sposto R, Meadows AT, Chilcote RR, Kjeldsberg C, Kadin ME, Krailo MD, Morse M, Siegel SE. Comparison of long-term outcome of children and adolescents with disseminated non-Hodgkin’s lymphoma treated with COMP or Daunomycin-COMP: A report from the Children’s Cancer Group. Med Pediatr Oncol, 37: 432-441, 2001.

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